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Gallium-68 generator : ウィキペディア英語版 | Gallium-68 generator A Germanium-68/Gallium-68 Generator is a device used to extract the positron-emitting isotope 68Ga of gallium from a source of decaying Germanium-68. The parent isotope 68Ge has a half-life of 271 days and can be easily utilized for in-hospital production of generator produced Ga-68. Its decay product Gallium-68 (with a half-life of only 68 minutes, inconvenient for transport) is extracted and used for certain positron emission tomography nuclear medicine diagnostic procedures, where the radioisotope's relatively short half-life and emission of positrons for creation of 3-dimensional PET scans, are useful. ==Parent isotope (Ge-68) source == The parent isotope Germanium-68 is the longest-lived (271 days) of the radioisotopes of germanium. It has been produced by several methods.〔(Note on Ge-68 production methods in 1996. Accessed March 15, 2010 )〕 In the U.S., it is primarily produced in proton accelerators: At Los Alamos National Laboratory, it may be separated out as a spallation product, after proton irradiation of molybdenum or rubidium. At Brookhaven National Laboratories, 40 MeV proton irradiation of a gallium metal target produces germanium-68 by proton capture and double neutron knockout, from Gallium-69 (the most common of two stable isotopes of gallium). This reaction is: Ga-69(p,2n)Ge-68. A Russian source produces Germanium-68 from accelerator-produced helium ion (alpha) irradiation of Zinc-66, again after knockout of two neutrons, in the nuclear reaction Zn-66(α,2n)Ge-68.
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